14.9%
Mean weight loss with semaglutide 2.4 mg
Over 68 weeks in the STEP-1 trial of 1,961 adults with overweight or obesity — vs. 2.4% with placebo.
STEP-1 · Wilding et al., NEJM 2021 ↗Starting at $149 · Free 1-2 Day Shipping · Cancel Anytime
GLP-1s Clinically Studied for Weight Management*
Weight loss, transformed.
Not another 30-day fix. A medically-guided weight management program — GLP-1 treatment designed around your body, your goals, and your life. Starting at $149. No hidden fees.
Up to 20.9% body weight loss in published GLP-1 trials*
US-licensed providers · US-based pharmacy · HIPAA compliant
Starting at $149 · no insurance · free 1-2 day shipping
No insurance required·Cancel anytime·Free discreet shipping
Available in 39 U.S. states · Licensed providers in your state
Be the first to review us on Trustpilot
LegitScriptCertified
Same-day provider response · Limited to 39 states
AvataCore Guarantee:30-day consultation refund·No membership fees·Cancel anytime
*Up to 20.9% average body weight loss over 72 weeks with tirzepatide 15mg in the SURMOUNT-1 trial (Jastreboff et al., N Engl J Med 2022); up to 14.9% over 68 weeks with semaglutide 2.4mg in the STEP-1 trial (Wilding et al., N Engl J Med 2021). Results are from studies of FDA-approved branded medications and may not reflect outcomes with compounded formulations. Individual results vary; weight loss is not guaranteed.
GLP-1 research cited in our clinical protocols
AvataCore treatment protocols are informed by clinical data from peer-reviewed research.
AvataCore is not affiliated with these publications.
14.9%
Avg. body weight reduction with semaglutide 2.4mg at 68 weeks1
20.9%
Avg. body weight reduction with tirzepatide 15mg at 72 weeks2
86%
Of STEP 1 participants lost ≥5% of body weight1
24/7
Licensed provider support via our clinical partner
1 Wilding et al., N Engl J Med 2021 (STEP 1) · 2 Jastreboff et al., N Engl J Med 2022 (SURMOUNT-1)
Individual results vary. Trial data does not guarantee outcomes.
Built for Clinical Trust
US-Licensed Providers
Board-certified MDs & NPs
HIPAA Compliant
End-to-end encryption
US-Based Pharmacy
State-licensed
HSA/FSA May Apply*
Use pre-tax dollars
30-Day Guarantee
Consultation refund if not prescribed
Personalized weight loss, guided by science.
Three clinically-backed paths. Take our 60-second quiz and a licensed provider matches you to the right one.
Personalized GLP-1
Weekly injection for steady appetite control and reliable weight loss.
Starting at $149
Personalized GLP-1 (Oral)
Daily dissolvable tablet for patients who prefer not to inject.
Starting at $149
Personalized GLP-1 + GIP
Dual-action weekly injection on two hormone pathways for more powerful results in some patients.
Starting at $199
*Eligibility required. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. See our Medication Options disclosure.
You’ve heard of these
Brand-name GLP-1 medications you may know
AvataCore does not dispense these branded products. We use compounded medications prepared by 503A state-licensed pharmacies under USP <797> standards and overseen by a licensed clinician.
Brand reference
01
Starting at $1,579
Wegovy® Tablets
Semaglutide · Daily tablet · Novo Nordisk
Learn why we use compounded →
Wegovy® is a registered trademark of Novo Nordisk. Not sold by AvataCore.
Brand reference
02
Starting at $1,579
Wegovy® Injection
Semaglutide · Weekly injection · Novo Nordisk
Learn why we use compounded →
Wegovy® is a registered trademark of Novo Nordisk. Not sold by AvataCore.
Brand reference
03
Starting at $1,249
Mounjaro® Injection
Tirzepatide · Weekly injection · Eli Lilly
Learn why we use compounded →
Mounjaro® is a registered trademark of Eli Lilly. Not sold by AvataCore.
Brand reference
04
Starting at $1,249
Zepbound® Injection
Tirzepatide · Weekly injection · Eli Lilly
Learn why we use compounded →
Zepbound® is a registered trademark of Eli Lilly. Not sold by AvataCore.
Brand reference
05
Starting at $1,149
Ozempic® Injection
Semaglutide · Weekly injection · Novo Nordisk
Learn why we use compounded →
Ozempic® is a registered trademark of Novo Nordisk. Not sold by AvataCore.
Brand-name medications shown for reference. AvataCore does not directly dispense Ozempic®, Wegovy®, Mounjaro®, or Zepbound®. Pricing reflects publicly available retail estimates and is subject to change. Compounded medications are different from FDA-approved branded products. AvataCore is not affiliated with Novo Nordisk or Eli Lilly.
Published Clinical Trial Outcomes
Average body weight reduction reported in peer-reviewed GLP-1 trials
Tirzepatide 15 mg
SURMOUNT-1 · 72 weeks · Jastreboff et al., NEJM 2022
20.9%
Semaglutide 2.4 mg
STEP-1 · 68 weeks · Wilding et al., NEJM 2021
14.9%
Placebo + lifestyle
Control arm reference (STEP/SURMOUNT pooled)
~3%
86%
Of STEP-1 participants achieved ≥5% body weight loss
2,539
Adults randomized in SURMOUNT-1 trial
68-72 wk
Treatment duration in pivotal trials
Trial data reflects FDA-approved branded formulations of semaglutide and tirzepatide. Compounded formulations are different from FDA-approved branded products and have not been evaluated by the FDA for safety, efficacy, or quality; outcomes with compounded preparations may differ. Individual results vary based on dose, adherence, diet, and other factors. Weight loss is not guaranteed. References: Wilding JPH et al., NEJM 384:989-1002 (2021); Jastreboff AM et al., NEJM 387:205-216 (2022).
Simple Process
Begin your weight loss journey with AvataCore.
Start your weight management journey today with AvataCore's easy, personalized process for accessing GLP-1 medications. Designed with your convenience in mind, our streamlined approach ensures you're supported every step of the way, from approval to receiving your prescription.
01
Today
Get Approved
Complete a quick online evaluation to determine if GLP-1 medication is right for you. Our team of licensed professionals will review your information and provide approval in no time.
02
Within 24 Hours
Get Prescribed
Once approved, you'll receive personalized care and a prescription to support your weight loss and health goals. Your care plan is designed to support your weight management journey under licensed-provider care.
03
In 3-7 Days
Receive your Rx
Your medication will be shipped directly to your door for maximum convenience. With AvataCore, starting your treatment is as simple as opening your package and following our easy-to-use instructions.
1-2 Day Free Delivery Available
Free to start · No credit card required
Unlimited 24/7 support included.
AvataCore provides 24/7 access to a dedicated team of specialists, ensuring you have the support you need around the clock. With unlimited appointments, messaging and support, you can confidently reach out for guidance, ask questions, or address concerns at any time.
Unlimited Messaging
Chat with your care team anytime
24/7 Availability
Support when you need it most
Dedicated Specialists
A team that knows your journey
No Extra Cost
All included in your plan
From Peer-Reviewed Research
What the clinical data actually shows.
Six findings from the pivotal GLP-1 trials that define how we build our care plans. No cherry-picked quotes — just the numbers from the peer-reviewed record.
20.9%
Mean weight loss with tirzepatide 15 mg
Over 72 weeks in the SURMOUNT-1 trial of 2,539 adults — the highest reduction in any published GLP-1 study to date.
SURMOUNT-1 · Jastreboff et al., NEJM 2022 ↗86%
Achieved ≥5% body weight loss
Clinically meaningful weight reduction threshold reached by the vast majority of STEP-1 participants — the benchmark providers care about.
STEP-1 · Wilding et al., NEJM 2021 ↗6×
More weight reduction observed in trials of FDA-approved formulations
Pooled GLP-1 trial arms showed 6× the weight reduction of placebo + lifestyle modification groups over the same duration.
STEP / SURMOUNT pooled control arms ↗~70%
Studies suggest much of weight regulation is biological
Appetite, satiety, and metabolic set point are largely governed by hormones — not willpower. GLP-1 works with your biology, not against it.
Obesity is a chronic disease · AMA 2013 ↗72 wk
Duration needed to see maximum effect
Pivotal trials run 68–72 weeks. Weight loss continues throughout — which is why our care plans are built for the long arc, not 30 days.
STEP-1 · SURMOUNT-1 ↗Take the Quiz →
Trial data reflects FDA-approved branded formulations. Compounded preparations are different from FDA-approved branded products and have not been evaluated by the FDA for safety, efficacy, or quality; outcomes may differ. Individual results vary. Weight loss is not guaranteed.
The AvataCore Guarantee
Cancel anytime. Money-back consultation guarantee.
If you're not satisfied with your initial provider consultation experience, we'll refund the consultation fee. Your treatment plan is determined by your licensed provider based on your medical history.
- Cancel anytime — no lock-in, no hidden fees
- Unlimited provider messaging for the life of your subscription
- No insurance needed · HSA/FSA eligible
Our Commitments
Our Guarantee to You
We only charge for care you can actually receive. Your trust is our top priority — from consultation to your door.
Free Shipping
Discreet packaging guaranteed
Consultation Refund Guarantee
If you are not a candidate for GLP-1 therapy after your provider consultation, you receive a full refund of your first payment — no questions asked.
Delivery Guarantee
If your medication is lost or damaged in transit, we will resend at no additional charge. We stand behind every shipment.
Privacy Guarantee
Your health information is protected under HIPAA and will never be sold. Plain, discreet packaging on every delivery.
Money-Back Guarantee on first consultation if not eligible
Real People. No Shame. All Confidence.
There’s no shame in asking for help with your weight.
Medical weight loss isn’t a shortcut — it’s evidence-based care for a chronic condition. Paired with thoughtful eating, movement you enjoy, and ongoing provider support, GLP-1 therapy can be a turning point for people who’ve been trying on their own for years.
You deserve a care team that takes you seriously, treats your body with respect, and meets you wherever you are on the journey.
Obesity is a chronic medical condition — not a willpower failure. You wouldn’t hesitate to treat high blood pressure or diabetes. Treating weight is no different.
— The AvataCore Care Team
Why we’re better at weight loss
Healthcare without the long wait times or doctor denials.
US-Licensed Pharmacies
Your medication is compounded by state-licensed sterile compounding pharmacies in the United States.
Personalized Treatment
A licensed provider matches you to the right molecule, dose, and titration plan based on your intake.
HIPAA-Compliant Platform
Built on Tellescope, a SOC 2 telehealth platform. Your records and messages are secure.
1:1 Care Team Support
Message your provider through your portal anytime. No phone tag, no waiting rooms.
AvataCore vs. Other Programs
One simple price. No hidden membership fees.
AvataCore
Other Programs
Pricing model
Transparent flat pricing
Membership fee + medication cost separate
Commitment
Cancel anytime
Multi-month commitments common
Insurance
Not required
Varies
Shipping
Free, 1-2 day, discreet
Varies; sometimes extra
Care team
1:1 messaging, included
Varies
GLP-1 Weight Loss by State
Connect with licensed providers in your state. Service available in 39+ U.S. states.
View all 50 states →Conditions We Address
Evidence-based information on weight-management conditions and GLP-1 therapy.
- Overweight & Obesity (BMI ≥27)
ICD-10 E66 · GLP-1 receptor agonist therapy for chronic weight management
- Semaglutide (Injectable & Oral)
Once-weekly injection or daily oral · GLP-1 receptor agonist
- Tirzepatide (Injectable)
Once-weekly injection · Dual GLP-1 + GIP receptor agonist
- Patient Education Library
Reviewed by OpenLoop Health clinicians
Ready to Start Losing Weight?
Start your weight management journey today. Our process is fast, simple, and backed by licensed providers.
Take the Quiz → It's FreeStarting at $149 · No membership fees · Cancel anytime